A P53-DEPENDENT RESPONSE LIMITS EPIDERMAL STEM CELL FUNCTIONALITY AND ORGANISMAL SIZE IN MICE WITH SHORT TELOMERES.

A p53-dependent response limits epidermal stem cell functionality and organismal size in mice with short telomeres.

Telomere maintenance is essential aluminum lotion to ensure proper size and function of organs with a high turnover.In particular, a dwarf phenotype as well as phenotypes associated to premature loss of tissue regeneration, including the skin (hair loss, hair graying, decreased wound healing), are found in mice deficient for telomerase, the enzyme

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Microstructure, mechanical properties and biomedical application of medical implantable extruded Mg-Zn-Zr-Ca alloy

This study added Zn, Zr and Ca as alloying elements of magnesium alloy (ZKX500) and produced fine grain structure by extrusion process.After 2 h of homogenization, abnormal grain growth was avoided, stress relief, improvement of stability and reduction of element segregation are sten jacket m achieved.In addition, application of phosphate coating o

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The Hagiographical Icon of Saint Nicholas in the Church of Michael the Brave from Ocna Sibiului. Iconographic, Artistic and Technical Issues

The article deals with some considerations upon the iconographic, artistic and technical issues that have been identified in the early 18th century hagiographical icon of Saint Nicholas from Transylvania.A description with references to the actual situation of the icon pictures the framework in which not only this object, but also a group of other

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